Chemistry at Illinois University of Illinois at Urbana-Champaign

Kami L. Hull

Assistant Professor of Chemistry

Professor Hull received her B.A. degree in chemistry from Macalester College in 2003. She obtained her Ph.D. from the University of Michigan in 2009, while there she received a ACS Division of Organic Chemistry Fellowship and the Roche Award for Excellence in Organic Chemistry. Upon graduation, she moved to California as an NIH postdoctoral fellow at Stanford University from 2009–2012. Professor Hull joined the faculty at the University of Illinois in the fall of 2012, and her research focuses on the development of and mechanistic studies on transition metal catalyzed reactions.

Research

As chemists we have developed the tools to access a wide array of complex organic structures; an ongoing challenge to organic chemists is to improve the efficiency of theses transformations by increasing both the step and atom economy. Research in the Hull group focuses on the development of transition metal-catalyzed reactions to access important organic products in a single step from easily accessible functionalities, ideally, without the generation of any stoichiometric byproducts. We aim to develop novel approaches to tradition bond disconnections, augmenting existing techniques. Mechanistic investigations help to guide the development of our synthetic methodologies.

Publications

[8.]Lyons, T. W.;Hull, K. L.;Sanford, M. S. “Controlling Site Selectivity in Pd-Catalyzed Oxidative Cross-Coupling Reactions,”J. Am. Chem. Soc.2011,133,4455-4464.

http://pubs.acs.org/doi/abs/10.1021/ja1097918?journalCode=jacsat&quickLinkVolume=133&quickLinkPage=4455&volume=133

[7.] Hull, K. L.;Sanford, M. S. “Mechanism of Benzoquinone-Promoted Palladium-Catalyzed Oxidative Cross-Coupling Reactions,”J. Am. Chem. Soc.2009,131,9651-9653.

http://pubs.acs.org/doi/abs/10.1021/ja901952h?journalCode=jacsat&quickLinkVolume=131&quickLinkPage=9651&volume=131

[6.] Hull, K. L.;Sanford, M. S. “Catalytic and Highly Regioselective Cross-Coupling of Aromatic C–H Substrates,”J. Am. Chem. Soc.2007,129,11904-11905.

[5.] Hull, K. L.;Lanni, E. L.; Sanford, M. S. “Highly Regioselective Catalytic Oxidative Coupling Reactions: Synthetic and Mechanistic Investigations,”J. Am. Chem. Soc.2006,128,14047-14049.

http://pubs.acs.org/doi/abs/10.1021/ja074395z?journalCode=jacsat&quickLinkVolume=129&quickLinkPage=11904&volume=129

[4.] Hull, K. L.;Anani, W. Q.; Sanford, M. S. “Palladium-Catalyzed Flourination of Carbon–Hydrogen Bonds,”J. Am. Chem. Soc.2006,128,7134-7135.

http://pubs.acs.org/doi/abs/10.1021/ja065718e?journalCode=jacsat&quickLinkVolume=128&quickLinkPage=14047&volume=128

[3.]Desai, L. V.;Hull, K. L.;Sanford, M. S. “Palladium-Catalyzed Oxygenation of Unactivated sp³C–H Bonds,”J. Am. Chem. Soc.2004,126,9542-9543.

http://pubs.acs.org/doi/abs/10.1021/ja046831c?journalCode=jacsat&quickLinkVolume=126&quickLinkPage=9542&volume=126

[2.]Dick, A. R.;Hull, K. L.;Sanford, M. S. “A Highly Selective Catalytic Method for the Oxidative Funtionalization of C–H Bonds,”J. Am. Chem. Soc.2004,126,2300-2301.

http://pubs.acs.org/doi/abs/10.1021/ja031543m?journalCode=jacsat&quickLinkVolume=126&quickLinkPage=2300&volume=126

[1.]Mio, M. J.; Kopel, L. C.; Braun, J. B.; Gadzikwa, T. L.;Hull, K. L.;Brisbois, R. G.; Markworth, C. J.; Grieco, P. A. “One-Pot Synthesis of Symmetrical and Unsymmetrical Bisarylethynes by a Modification of the Sonogashira Coupling Reaction,”Org. Lett.2002,4,3199-3202.

http://pubs.acs.org/doi/abs/10.1021/ol026266n?journalCode=orlef7&quickLinkVolume=4&quickLinkPage=3199&volume=4

Awards

2016 Sloan Research Fellow

2016 NSF Faculty Early Career Development (CAREER) Award

Kasimir Fajans Award in Chemistry, 2011

NIH Postdoctoral Fellowship, 2009-12

Roche Excellence in Chemistry Award, 2008

Writ and Mary Cornwell Outstanding Graduate Student Research Award, 2007

ACS Division of Organic Chemistry Fellowship, Eli Lilly, 2006

Novartis Graduate Fellowship, 2005

Chemical Sciences at the Interface of Education NSF-GAANN Fellowship, 2004

Wallace Undergraduate Summer Research Fellowship, Macalester College, 2002

Highlights

coming soon

Patents

coming soon
Kami L. Hull photo